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Trial record: BI 456906 versus semaglutide receptor activity

Registry status checked on 3 October 2026: active not recruiting.

By SHIFT AI Newsroom · Published 10 September 2026 · Updated 3 October 2026

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ClinicalTrials.gov lists NCT05202353, concerning BI 456906 versus semaglutide receptor activity, as active not recruiting. The record was first posted on 2022-01-21 and last updated on 2026-09-09; SHIFT checked it on 3 October 2026. This means the study remains active but is not currently enrolling new participants.

This phase 1 study measures receptor activity using imaging. It should not be presented as a weight-loss efficacy comparison.

No results tables were posted in this registry record when checked. That does not establish that no results have been published elsewhere. A registry entry is not a UK marketing authorisation or confirmation of NHS access.

SHIFT’s take

What we think this could mean for you, and what remains uncertain.

Keep the trial status, published results and UK treatment access separate. Do not change treatment on the basis of a registration.

Sources and evidence

ClinicalTrials.gov — Source date: 2 September 2026

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