ONCE-DAILY TABLET
Wegovy tablet
Oral semaglutide. A modern, needle-free route with specific daily instructions.
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OPTIONS WORTH UNDERSTANDING
Medication worth understanding.
CAPSULES WITH MEALS
Orlistat
A needle-free, non-GLP-1 route with meal-linked dosing and a lower price.
ONCE-WEEKLY INJECTION
Mounjaro
Tirzepatide. One small injection each week with staged dose options.
ONCE-WEEKLY INJECTION
Wegovy injection
Semaglutide. One small injection each week with gradual dose increases.
NEW ONCE-DAILY TABLET
Foundayo
Orforglipron. A newly authorised, needle-free daily route without fasting rules; Shift supply remains locked.
WEGOVY TABLET · QUICK GUIDENeedle-free, but it needs a daily routine.
- 01 · Frequency
- One tablet every day, with specific fasting and administration instructions.
- 02 · Starting route
- Normally 1.5 mg daily, increasing in stages when clinically appropriate.
- 03 · Eligibility
- Usually BMI 30+, or BMI 27–29.9 with a qualifying weight-related condition.
- 04 · The appeal
- Modern semaglutide treatment without injections.
- 05 · The trade-off
- Daily dosing and administration rules need more routine than a weekly injection.
ORLISTAT · QUICK GUIDENeedle-free and non-GLP-1.
- 01 · Frequency
- A 120 mg capsule taken as directed with suitable meals containing fat.
- 02 · Dose route
- The strength does not climb; customers select the required pack size.
- 03 · Eligibility
- Usually BMI 30+, or BMI 28+ with associated health risks.
- 04 · The appeal
- A lower-cost, needle-free medicine that works differently from appetite medicines.
- 05 · The trade-off
- Meal-linked dosing and digestive side effects can make it less convenient.
MOUNJARO · QUICK GUIDEPowerful weekly treatment with a staged dose route.
- 01 · Frequency
- One small injection each week.
- 02 · Starting route
- Normally 2.5 mg weekly, increasing gradually when appropriate.
- 03 · Eligibility
- Usually BMI 30+, or BMI 27–29.9 with a qualifying condition.
- 04 · The appeal
- Strong average weight-loss evidence and only one dose each week.
- 05 · The trade-off
- An injection with gastrointestinal side effects and staged dosing.
WEGOVY INJECTION · QUICK GUIDEEstablished semaglutide treatment, taken weekly.
- 01 · Frequency
- One small injection each week.
- 02 · Starting route
- Normally 0.25 mg weekly, increasing gradually when appropriate.
- 03 · Eligibility
- Usually BMI 30+, or BMI 27–29.9 with a qualifying condition.
- 04 · The appeal
- Substantial longer-term evidence with once-weekly dosing.
- 05 · The trade-off
- An injection, gradual titration and response that varies between people.
FOUNDAYO · QUICK GUIDEThe new daily GLP-1 tablet without fasting rules.
- 01 · Frequency
- One tablet every day.
- 02 · Starting route
- A staged route beginning at 0.8 mg daily, subject to prescriber confirmation.
- 03 · Eligibility
- Usually BMI 30+, or BMI 27–29.9 with a qualifying weight-related condition.
- 04 · The appeal
- Needle-free, with no fasting or water restriction around the dose.
- 05 · The trade-off
- It is new, has less real-world experience and Shift supply is not yet confirmed.
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This guidance is a starting point, not a diagnosis or treatment recommendation. Suitability, medicine and dose can only be confirmed after an appropriate clinical assessment by a regulated prescribing service.