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Research suggests females may be resistant to semaglutide-induced muscle loss

A study on ob/ob mice found that females are completely resistant to semaglutide-induced muscle loss, according to research published on Europe PMC

Published 2026-09-10 · Evidence level 2

Research published on Europe PMC has found that females are completely resistant to semaglutide-induced muscle loss in ob/ob mice. This study may have implications for the use of semaglutide in humans, particularly in terms of potential side effects and gender-specific responses.

What this means in the UK

This research may have implications for the use of semaglutide in humans, particularly in terms of potential side effects and gender-specific responses

Known facts

  • Females are completely resistant to semaglutide-induced muscle loss in ob/ob mice

Sources and evidence

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